What is Vetoryl and what does it do?
Vetoryl is a prescription medication that is used to control cortisol production in dogs in order to treat Cushing's Disease (hyperadrenocorticism). The main ingredient in Vetoryl, trilostane, inhibits the conversion of pregnenolone to progesterone to block the production of glucocorticoids, sex hormones, and mineralocorticoids while steroid precursor levels increase. While Vetoryl cannot cure Cushing's Disease, it is an important part of the long-term management of the symptoms.
Why would my dog need Vetoryl?
Your veterinarian might recommend putting your dog on Vetoryl if they have pituitary-dependent or adrenal-dependent Cushing's Disease.
What else should I discuss with my veterinarian while considering Vetoryl?
Vetoryl and Cushing's Disease require long-term monitoring and frequent tests. Be sure to ask what signs your dog should show while on Vetoryl and when to contact your veterinarian. Also, find out what kinds of tests and exams will be necessary to monitor your pet's condition. You should also use this time to discuss the possible risks associated with Vetoryl and tell your veterinarian about any other medications or over-the-counter supplements your pet may be taking. Also inform your veterinarian if your pet has any kidney or liver diseases.
What are the side effects?
The most common side effects of Vetoryl Capsules include: decreased appetite, vomiting, diarrhea, and weakness/lethargy. The following serious adverse effects are more rare: depression, bloody diarrhea, collapse, hypoadrenocortical crisis, adrenal necrosis/rupture, or other severe reactions that may lead to death.
What should I do if a side effect occurs?
If you observe an adverse reaction to Vetoryl in your dog, discontinue use and contact your veterinarian immediately.
What should I do if I miss a dose?
If you miss giving your dog a dose, give it as soon as you remember. If it is almost time for the next dose, skipped the missed one and get back on the regular Vetoryl dosing schedule. Do not give two doses at once.
How far apart should I give Vetoryl?
Vetoryl is designed to be given once daily. However, some dogs may not respond to just once a day dosing. If the clinical signs of Cushing's Disease are not controlled for a full day, discuss with your veterinarian if they think administering Vetoryl twice daily is necessary.
Can I open the Vetoryl capsules?
Vetoryl should be administered whole and with food. Do not break the capsules open. If your dog does not like taking the medication, try hiding the capsules in Greenies Pill Pockets or a similar product.
Does Vetoryl work for life?
Vetoryl is not a cure for Cushing's Disease, but it can help control the various symptoms. In most cases, treatment with Vetoryl will need to continue for life. If use of the medication is discontinued, the signs of hyperadrenocorticism will reappear.
Trilostane vs Vetoryl
Trilostane is the name of the drug in Vetoryl. However, there is no generic alternative to Vetoryl.
Will Vetoryl affect my dog's diabetes?
Vetoryl is not used to treat diabetes or control blood sugar levels. If your dog has diabetes and Cushing's Disease you should be in close contact with your veterinarian to make sure your pet gets the best treatment that's right for them.
Who manufactures Vetoryl?
Vetoryl is manufactured by Dechra Veterinary Products.
What do I do if my dog on Vetoryl has intermittent urinary tract infections?
During a US field study, urinary tract infections were recorded in some of the dogs taking Vetoryl. If your dog has intermittent UTIs while on Vetoryl, consult with your veterinarian.
Can I give my dog Vetoryl and Selegiline?
You should discuss this with your veterinarian. Talk to them about any other medications or over-the-counter supplements your pet may be taking. Do not adjust doses or begin administering new medications to your pet without their approval.
Can a pregnant woman administer Vetoryl?
The manufacturer's label and packaging materials state that women who are pregnant or trying to conceive should not handle Vetoryl capsules.
Why did my veterinarian recommended Lysodren instead of Vetoryl?
Both Lysodren and Vetoryl are used to treat Cushing's Disease in dogs, but they work differently. Which one will work best for your pet depends on the type of Cushing's Disease they have, its severity, and many other factors. You should ask your veterinarian why they may have chosen one treatment option over another.
Can you liquify Vetoryl?
If you are having trouble getting your dog to take the Vetoryl capsules, try hiding them inside a Greenies Pill Pocket or other similar product. If that does not work, consult with your veterinarian.