I loved this product but found it too late to save my dog. she had renal failure at 13.5 yrs old with autoimmune disease which caused a rapid decline and her death this past week. When I started her on Renal 2 wks ago, she stopped vomiting and her stools changed from diahhrea to normal. this allowed her to intake more food which made her stronger. But it was all too late. Her bun/creatine scores still declined by 20 points. Vet said renal could do no harm and continue, which I did. But she's gone now; but I did all I could. In her honor, I donated the renal to a friend who's 14 yr old dog has kidney flush discomfort during the night. It has already appeared to help him. I will test my other 12 yr old dog soon and if any renal decline, I will start her on this product immediately. thank you.