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I use about an inch of this on the gum-line of my dog after brushing with enzymatic chicken flavored paste if his gums are red/bleeding or if there was significant tarter build up. I brush his teeth about every 2 to 3 days so this is rare, but sometimes happens. It seems to make the next brushing event easier and breaks down the plaque.
For years, our twelve year old 6 pound dog has required 2 people to do a sub-optimal job of brushing his teeth. The vet would talk to me like I was irresponsible, and finally I asked HIM to show me a way I could brush his teeth alone. He managed, but also had the vet intimidation on his side. That technique only worked a couple of times before the amazingly great evasive maneuvers returned. Also valuing my relationship with my pet, I did not want to hurt him. I had starting as you are supposed to, when he was a baby, allowing him to lick toothpaste off my finger. He just never accepted the brush, of any kind. He has lost teeth, as his breed is prone to dental problems. I am happy to say he is likely this new "brush-less" method, which I stumbled upon because I like Biotene products for myself. Now, I just have to hope the next dental exam will show we are good in that department!
This product is Great! Sammy will not let me get close to his mouth with a toothbrush, this is so much easier and it does not upset his stomach (as other oral products for dogs have).